KEGG   Homo sapiens (human): 2582
Entry
2582              CDS       T01001                                 
Symbol
GALE, SDR1E1
Name
(RefSeq) UDP-galactose-4-epimerase
  KO
K01784  UDP-glucose 4-epimerase [EC:5.1.3.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00052  Galactose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
hsa01100  Metabolic pathways
hsa01250  Biosynthesis of nucleotide sugars
Module
hsa_M00632  Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
Network
nt06023  Galactose degradation
  Element
N00847  Galactose degradation
Disease
H00070  Galactosemia
H00978  Thrombocytopenia (THC)
H02010  Galactose epimerase deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    2582 (GALE)
   00520 Amino sugar and nucleotide sugar metabolism
    2582 (GALE)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.2  UDP-glucose 4-epimerase
     2582 (GALE)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase 3Beta_HSD RmlD_sub_bind Polysacc_synt_2 NAD_binding_4 KR NAD_binding_10 NmrA adh_short
Other DBs
NCBI-GeneID: 2582
NCBI-ProteinID: NP_000394
OMIM: 606953
HGNC: 4116
Ensembl: ENSG00000117308
UniProt: Q14376 A0A384NL38
Structure
Position
1:complement(23795599..23800754)
AA seq 348 aa
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
NT seq 1047 nt   +upstreamnt  +downstreamnt
atggcagagaaggtgctggtaacaggtggggctggctacattggcagccacacggtgctg
gagctgctggaggctggctacttgcctgtggtcatcgataacttccataatgccttccgt
ggagggggctccctgcctgagagcctgcggcgggtccaggagctgacaggccgctctgtg
gagtttgaggagatggacattttggaccagggagccctacagcgtctcttcaaaaagtac
agctttatggcggtcatccactttgcggggctcaaggccgtgggcgagtcggtgcagaag
cctctggattattacagagttaacctgaccgggaccatccagcttctggagatcatgaag
gcccacggggtgaagaacctggtgttcagcagctcagccactgtgtacgggaacccccag
tacctgccccttgatgaggcccaccccacgggtggttgtaccaacccttacggcaagtcc
aagttcttcatcgaggaaatgatccgggacctgtgccaggcagacaagacttggaacgca
gtgctgctgcgctatttcaaccccacaggtgcccatgcctctggctgcattggtgaggat
ccccagggcatacccaacaacctcatgccttatgtctcccaggtggcgatcgggcgacgg
gaggccctgaatgtctttggcaatgactatgacacagaggatggcacaggtgtccgggat
tacatccatgtcgtggatctggccaagggccacattgcagccttaaggaagctgaaagaa
cagtgtggctgccggatctacaacctgggcacgggcacaggctattcagtgctgcagatg
gtccaggctatggagaaggcctctgggaagaagatcccgtacaaggtggtggcacggcgg
gaaggtgatgtggcagcctgttacgccaaccccagcctggcccaagaggagctggggtgg
acagcagccttagggctggacaggatgtgtgaggatctctggcgctggcagaagcagaat
ccttcaggctttggcacgcaagcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (6)   
   KEGG DISEASE (3)   
   OMIM (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (3)   
   GenBank (14)   
   EMBL (14)   
3D Structure (7)   
   PDB (7)   
Protein domain (10)   
   Pfam (10)   
All databases (93)   

Download RDF
DBGET integrated database retrieval system